Immunology Video Lectures

 

 

 

HHMI Howard Hughes Medical Institute - BioInteractive

Presented by HHMI investigators John W. Kappler, Ph.D., and Philippa Marrack, Ph.D.

View the webcast video of the 1996 Holiday Lectures on Science. Choose your connection speed below. Requires RealPlayer.

  • Lecture One—How Immune Cells Create Trillions of Receptors from a Few Hundred Parts by John W. Kappler, Ph.D.
                          56k modem or Cable/DSL/T1

  • Lecture Two—How the Immune System Detects Invaders by Philippa Marrack, Ph.D.
                          56k modem or Cable/DSL/T1

  • Lecture Three—How the Host Avoids 'Friendly Fire' by John W. Kappler, Ph.D.
                          56k modem or Cable/DSL/T1

  • Lecture Four—Stalking the Elusive Pathogen by Philippa Marrack, Ph.D.
                          56k modem or Cable/DSL/T1

Immunology: Informal Talks

Rheumatoid Arthritis: Past, Present, and Future

Andrew C. Chan, M.D., Ph.D.
Associate Investigator, Washington University School of Medicine

Requires RealOne Player

How is science unraveling the mysteries of autoimmune diseases? Rheumatologist Andrew Chan, M.D., Ph.D., a former HHMI investigator at the Washington University School of Medicine, discusses advances in understanding and treating rheumatoid arthritis, a chronic and debilitating disease. After describing past and present treatments for the disease, Chan looks to the future and explains how current research in understanding the immune system is leading to new drug therapies. The lecture, videotaped at HHMI headquarters, is indexed by content. An animation on the proliferation of the T cell, slides, and questions from a studio audience enhance the talk. The animation with background information and detailed text is also available at this website.

UT-Houston Medical School Immunology PowerPoint Lectures

Introduction Antibodies and T Cell Receptors - Structure and Activities Cellular Activities Medical Applications of Immunology

Life Sciences/HHMI Outreach Program

 

"The Role of Innate & Adaptive Immunity in the Response to Pathogens"
Dr. Michael Carroll
Professor of Pediatrics & (Pathology) Harvard Medical School,
The CBR Institute for Biomedical Research
Dr. Carroll will describe basic concepts in innate and adaptive immunity and how the two systems work synergistically. His discuss will focus on a murine model in which the innate immune system enhances the antibody response to an infectious viral agent (herpes simplex virus).
"T-cell responses to Microbial Pathogens"
Dr. Michael Starnbach
Department of Microbiology and Molecular Genetics,
Harvard Medical School
Bacterial pathogens have devised a great number of virulence strategies that allow them to successfully use animal hosts to replicate and spread. These strategies also dictate the types of immune responses that are effective at eliminating these organisms. The lecture will focus on how the adaptive immune system responds to bacterial pathogens.
"Harnessing RNA Interference for Therapy"
Dr. Judy Lieberman
Senior Investigator and Professor of Pediatrics,
The CBR Institute for Biomedical Research, Harvard Medical School
RNA interference is a recently described process for silencing gene expression that occurs in all cells. RNA interference uses small double stranded RNAs to target messenger RNAs with homologous sequences for degradation. Dr. Lieberman will discuss how these small RNAs might be used as drugs to treat a variety of human diseases.
"Innate Immunity in Tropical Disease"
Dr. Donald Harn
Professor, Department of Immunology and Infectious Diseases,
Harvard School of Public Health
Dr. Harn will discuss the activation of "immune" cells by a family of oligosaccharides that are expressed on a variety of pathogen surfaces, including the human helminth parasite Schistosoma mansoni. The role of toll-like receptors in immune responses to tropical parasites, and the development of vaccines for infectious diseases of the tropics will also be explored.
"Co-option and Destruction of the Immune System by HIV"
Dr. Robert Lue
Dean of the Harvard Summer School,
Senior Lecturer on Molecular and Cellular Biology,
Director of HHMI Undergraduate & Outreach Programs at Harvard
Conservative estimates indicate that more than 40 million men, women, and children are currently infected with HIV world-wide. The vast majority of these individuals will go on to develop AIDS and become part of the most serious medical crisis in recorded history. Dr. Lue will discuss the diverse ways in which the virus and viral proteins both co-opt and ultimately destroy the human immune system.

 

"Differentiation and Function of CD4"
Dr. Laurie Glimcher
Higgins Professor of Biochemistry,
Department of Molecular and Cellular Biology
Click For Video
"Adaptive Immune Responses to Bacterial Pathogens"
Dr. Michael Starnbach
Associate Professor of Microbiology and Molecular Genetics,
Harvard Medical School
Bacterial pathogens have devised a great number of virulence strategies that allow them to successfully use animal hosts to replicate and spread. These strategies also dictate the types of immune responses that are effective at eliminating these organisms. The lecture will focus on how the adaptive immune system responds to bacterial pathogens.
"Natural Killer Cells"
Dr. Jack Strominger
Higgins Professor of Biochemistry,
Department of Molecular and Cellular Biology